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How do embryos establish reproducible spatial patterns of gene expression from stochastic transcription?
Histone variant H2A.B-H2B dimers are spontaneously exchanged through the open conformation with canonical H2A-H2B in the nucleosome
How does the genome change as we age?
Elucidation of the role of a protein that supports the matching of paternal and maternal chromosomes in meiosis
Elucidation of the mechanism by which cGAS, a foreign DNA sensor of innate immunity, does not respond to self chromosomal DNA
Elucidation of the DNA binding mechanism of GATA3, a transcription factor regulating cell fate
Successful development of technology for simultaneous detection of multiple epigenomic information from the same cell
Development of a new analysis method for accurate evaluation of protein structure in solution
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List of researchers
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Research Division for Quantitative Life Sciences
Laboratory of Genome Structure and Function
Katsuhiko Shirahige
Laboratory of Membrane Proteins
Chikashi Toyoshima
Laboratory of Chromatin Structure and Function
Hitoshi Kurumizaka
Laboratory of Molecular Neurobiology
Yusuke Kishi
Laboratory of chromosome configuration
Camilla Björkegren
Research Division for Applied Life Sciences
Laboratory of Pathology and Development
Yuki Okada
Laboratory of Immunology and Infection Control
Reiko Shinkura
Laboratory of Molecular Immunology
Taku Okazaki
Laboratory of RNP Synthetic Biology and Biotechnology
Hirohide Saito
Laboratory of Immunology and Immunopathology
Shunsuke Chikuma
Laboratory of Epithelial-Mesenchymal Plasticity
Ruby Yun-Ju Huang
Laboratory of Rare Disease Research
Kosuke Izumi
Research Center for Biological Visualization
Laboratory of Genome Regeneration
Takehiko Kobayashi
Laboratory of Transcription Dynamics
Takashi Fukaya
Laboratory of DNA Topology and Genome Maintenance
Kristian Jeppsson
Laboratory of Functional Nuclear Imaging
Hiroshi Kimura
Laboratory of Epitranscriptomics
Tsutomu Suzuki
Research Center for Cellular Dynamics
Laboratory of Molecular and Genetic Information
Tetsu Akiyama
Laboratory of Cell Growth and Differentiation
Atsushi Miyajima
Laboratory of RNA Function
Yukihide Tomari
Laboratory of Stem Cell Regulation
Minoru Tanaka
Laboratory of Behavioral Neuroscience
Teruhiro Okuyama
Laboratory of Computational Genomics
Ryuichiro Nakato
Laboratory of Neural Computation
Akihiro Funamizu
Laboratory of mRNA Translation
Hotaka Kobayashi
Laboratory of Oncoprotein Kinetics
Donald Cameron
Laboratory of Molecular Design
Björn Högberg
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