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Pressrelease

Elucidation of the functional ligand of LAG-3, a potential therapeutic target of cancer immunotherapy
PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity
Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant
Regulation of transcriptional bursting by core promoter elements
HiC1Dmetrics: framework to extract various one-dimensional features from chromosome structure data
Drug screening model of therapeutic agents for liver fibrosis using hiPSC-derived quiescent hepatic stellate cells
Development of magnetic beads suitable for a next-generation epigenome analysis method CUT&Tag
Development of an Epigenomic Analysis Method for Minor Cell Populations in Tissue
PD-1 preferentially inhibits the activation of low affinity T cells
Sequence homogeneity is highly controlled in human ribosomal RNA gene cluster

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List of researchers

List of research groups

Research Division for Quantitative Life Sciences

  • Laboratory of Genome Structure and Function
    Katsuhiko Shirahige
  • Laboratory of Membrane Proteins
    Chikashi Toyoshima
  • Laboratory of Chromatin Structure and Function
    Hitoshi Kurumizaka
  • Laboratory of Bioinformatics
    Wataru Iwasaki
  • Laboratory of Genetic Networks
    Charles M. Boone

Research Division for Applied Life Sciences

  • Laboratory of Pathology and Development
    Yuki Okada
  • Laboratory of Immunology and Infection Control
    Reiko Shinkura
  • Laboratory of Molecular Immunology
    Taku Okazaki
  • Laboratory of ALA Advanced Medical Research
    Kenzaburo Tani
  • Laboratory of Rare Disease Research
    Kosuke Izumi
  • Laboratory of Bioinformatics and Computational Physics
    Kentaro Shimizu

Research Center for Biological Visualization

  • Laboratory of Neuroscience
    Tetsuya Tabata
  • Laboratory of Genome Regeneration
    Takehiko Kobayashi
  • Laboratory of Transcription Dynamics
    Takashi Fukaya
  • Laboratory of Functional Nuclear Imaging
    Hiroshi Kimura
  • Laboratory of Epitranscriptomics
    Tsutomu Suzuki

Research Center for Cellular Dynamics

  • Laboratory of Molecular and Genetic Information
    Tetsu Akiyama
  • Laboratory of Cell Growth and Differentiation
    Atsushi Miyajima
  • Laboratory of RNA Function
    Yukihide Tomari
  • Laboratory of Stem Cell Regulation
    Minoru Tanaka
  • Laboratory of Behavioral Neuroscience
    Teruhiro Okuyama
  • Laboratory of Computational Genomics
    Ryuichiro Nakato
  • Laboratory of Neural Computation
    Akihiro Funamizu
  • UTokyo Foundation
  • Council for Research Institutes and Centers of Japanese National Universities
  • The University of Tokyo
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