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Pressrelease

Unveiling the roles of non-coding enhancer transcription in living Drosophila embryos
Spt4 promotes cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters
Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1
Cryo-electron microscopic analysis reveal a novel structural unit of chromatin, H3-H4 octasome
CohesinDB: A comprehensive database for decoding cohesin-related epigenomes, 3D genomes and transcriptomes in human cells
Structural basis for the nucleosome binding by “Guardian of the genome” p53
Elucidation of the structural basis for binding of acetyltransferase p300 to the nucleosome
Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation
Elucidation of the functional ligand of LAG-3, a potential therapeutic target of cancer immunotherapy
PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity

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List of researchers

List of research groups

Research Division for Quantitative Life Sciences

  • Laboratory of Genome Structure and Function
    Katsuhiko Shirahige
  • Laboratory of Membrane Proteins
    Chikashi Toyoshima
  • Laboratory of Chromatin Structure and Function
    Hitoshi Kurumizaka
  • Laboratory of Molecular Neurobiology
    Yusuke Kishi
  • Laboratory of Bioinformatics
    Wataru Iwasaki
  • Laboratory of Genetic Networks
    Charles M. Boone

Research Division for Applied Life Sciences

  • Laboratory of Pathology and Development
    Yuki Okada
  • Laboratory of Immunology and Infection Control
    Reiko Shinkura
  • Laboratory of Molecular Immunology
    Taku Okazaki
  • Laboratory of ALA Advanced Medical Research
    Kenzaburo Tani
  • Laboratory of Rare Disease Research
    Kosuke Izumi
  • Laboratory of Bioinformatics and Computational Physics
    Kentaro Shimizu

Research Center for Biological Visualization

  • Laboratory of Neuroscience
    Tetsuya Tabata
  • Laboratory of Genome Regeneration
    Takehiko Kobayashi
  • Laboratory of Transcription Dynamics
    Takashi Fukaya
  • Laboratory of Functional Nuclear Imaging
    Hiroshi Kimura
  • Laboratory of Epitranscriptomics
    Tsutomu Suzuki

Research Center for Cellular Dynamics

  • Laboratory of Molecular and Genetic Information
    Tetsu Akiyama
  • Laboratory of Cell Growth and Differentiation
    Atsushi Miyajima
  • Laboratory of RNA Function
    Yukihide Tomari
  • Laboratory of Stem Cell Regulation
    Minoru Tanaka
  • Laboratory of Behavioral Neuroscience
    Teruhiro Okuyama
  • Laboratory of Computational Genomics
    Ryuichiro Nakato
  • Laboratory of Neural Computation
    Akihiro Funamizu
  • UTokyo Foundation
  • Council for Research Institutes and Centers of Japanese National Universities
  • The University of Tokyo
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