- Combining a statistical model that evaluates the mobility of molecules, we have established a new analysis technology that can analyze the epigenomic information of an entire tissue, including minority cells buried in majority cells, such as stem cells.
- Highly sensitive and accurate epigenomic information can be obtained from a single thin tissue section of 3 mm x 3 mm x 10 μm.
- This method reduces cell loss and stresses on cells less than conventional methods.
Pressrelease
(Go to the IQB Japanese Website)
Journals
Journal:
Molecular Systems Biology. 2021
Title: Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections
Author: Kazumitsu Maehara, Kosuke Tomimatsu, Akihito Harada, Kaori Tanaka, Shoko Sato, Megumi Fukuoka, Seiji Okada, Tetsuya Handa, Hitoshi Kurumizaka, Noriko Saitoh, Hiroshi Kimura, and Yasuyuki Ohkawa
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DOI:
10.15252/msb.202110323
