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Pressrelease

The proper spacing between active replication origins ensures genome stability
How do embryos establish reproducible spatial patterns of gene expression from stochastic transcription?
Histone variant H2A.B-H2B dimers are spontaneously exchanged through the open conformation with canonical H2A-H2B in the nucleosome
How does the genome change as we age?
Elucidation of the role of a protein that supports the matching of paternal and maternal chromosomes in meiosis
Elucidation of the mechanism by which cGAS, a foreign DNA sensor of innate immunity, does not respond to self chromosomal DNA
Elucidation of the DNA binding mechanism of GATA3, a transcription factor regulating cell fate
Successful development of technology for simultaneous detection of multiple epigenomic information from the same cell
Development of a new analysis method for accurate evaluation of protein structure in solution

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List of researchers

List of research groups

Research Division for Quantitative Life Sciences

  • Laboratory of Genome Structure and Function
    Katsuhiko Shirahige
  • Laboratory of Membrane Proteins
    Chikashi Toyoshima
  • Laboratory of Chromatin Structure and Function
    Hitoshi Kurumizaka
  • Laboratory of Molecular Neurobiology
    Yusuke Kishi
  • Laboratory of chromosome configuration
    Camilla Björkegren

Research Division for Applied Life Sciences

  • Laboratory of Pathology and Development
    Yuki Okada
  • Laboratory of Immunology and Infection Control
    Reiko Shinkura
  • Laboratory of Molecular Immunology
    Taku Okazaki
  • Laboratory of RNP Synthetic Biology and Biotechnology
    Hirohide Saito
  • Laboratory of Immunology and Immunopathology
    Shunsuke Chikuma
  • Laboratory of Epithelial-Mesenchymal Plasticity
    Ruby Yun-Ju Huang
  • Laboratory of Nucleic Acid Nanotechnology
    Yusuke Sakai
  • Laboratory of Rare Disease Research
    Kosuke Izumi

Research Center for Biological Visualization

  • Laboratory of Genome Regeneration
    Takehiko Kobayashi
  • Laboratory of Transcription Dynamics
    Takashi Fukaya
  • Laboratory of DNA Topology and Genome Maintenance
    Kristian Jeppsson
  • Laboratory of Functional Nuclear Imaging
    Hiroshi Kimura
  • Laboratory of Epitranscriptomics
    Tsutomu Suzuki

Research Center for Cellular Dynamics

  • Laboratory of Molecular and Genetic Information
    Tetsu Akiyama
  • Laboratory of Cell Growth and Differentiation
    Atsushi Miyajima
  • Laboratory of RNA Function
    Yukihide Tomari
  • Laboratory of Behavioral Neuroscience
    Teruhiro Okuyama
  • Laboratory of Computational Genomics
    Ryuichiro Nakato
  • Laboratory of Neural Computation
    Akihiro Funamizu
  • Laboratory of mRNA Translation
    Hotaka Kobayashi
  • Laboratory of Oncoprotein Kinetics
    Donald Cameron
  • Laboratory of Molecular Design
    Björn Högberg
  • UTokyo Foundation
  • Council for Research Institutes and Centers of Japanese National Universities
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