Pressrelease

2020-09-11 / Last updated : 2021-02-04 adiqb1 Laboratory of Chromatin Structure and Function

Elucidation of the mechanism by which cGAS, a foreign DNA sensor of innate immunity, does not respond to self chromosomal DNA

Hitoshi KURUMIZAKA
Science

 

 

Journals

Journal: Science
Title: Structural basis for the inhibition of cGAS by nucleosomes
Author: Tomoya Kujirai†, Christian Zierhut†, Yoshimasa Takizawa, Ryan Kim,Lumi Negishi, Nobuki Uruma, Seiya Hirai, Hironori Funabiki＊, Hitoshi Kurumizaka＊
DOI: 10.1126/science.abd0237

 

Pressrelease
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Laboratory of Chromatin Structure and Function
Professor
Hitoshi Kurumizaka