2007年
"Origin of chemoselectivity of TMP zincate bases and differences between
TMP zincate and alkyl lithium reagents: A DFT study on model systems"
Masanobu Uchiyama, Yotaro Matsumoto, Shinya Usui, Yuichi Hashimoto and Keiji Morokuma
Angew. Chem. Int. Ed. 2007, 46(6), 926-929. |
"Hydrolyzed Metabolites of Thalidomide: Synthesis and TNF-α Production-Inhibitory
Activity"
Takanori Nakamura, Tomomi Noguchi, Hiroyuki Miyachi and Yuichi Hashimoto
Chem. Pharm. Bull., 2007, 55(4), 651-654. |
"Theoretical Studies on ortho-Oxidation of Phenols with Dioxygen Mediated by Dicopper Complex: Hints
for a Catalyst with the Phenolase Activity of Tyrosinase"
Hiroshi Naka, Yoshinori Kondo, Shinya Usui, Yuichi Hashimoto, Masanobu
Uchiyama
Adv. synth. Catal., 2007, 349(4-5), 595-600. |
"Structural development studies of nuclear receptor ligands"
Shinnosuke Hosoda and Yuichi Hashimoto
Pure Appl. Chem., 2007, 79(4), 615-626. |
"Development of Tubulin-Polymerization Inhibitors Based on the Thalidomide Skeleton"
Hiroshi Aoyama, Tomomi Noguchi, Takashi Misawa, Takanori Nakamura, Hiroyuki
Miyachi, Yuichi Hashimoto and Hisayoshi Kobayashi
Chem. Pharm. Bull., 2007, 55(6), 944-949. |
"Liver X receptor antagonists with a phthalimide skeleton derived
from thalidomide-related glucosidase inhibitors"
Tomomi Noguchi-Yachide, Atsushi Aoyama, Makoto Makishima, Hiroyuki Miyachi and
Yuichi Hashimoto
Bioorg. Med. Chem. Lett., 2007, 17(14), 3957-3961. |
"Design, synthesis, and evaluation of potent, structurally novel
peroxisome proliferator-activated receptor (PPAR) δ-selective
agonists"
Jun-ichi Kasuga, Izumi Nakagome, Atsushi Aoyama, Kumiko Sako, Michiyasu
Ishizawa, Michitaka Ogura, Makoto Makishima, Shuichi Hirono, Yuichi Hashimoto
and Hiroyuki Miyachi
Bioorg. Med. Chem., 2007, 15(15), 5177-5190. |
"Design, synthesis, and evaluation of isoindolinone-hydroxamic
acid derivatives as histone deacetylase (HDAC) inhibitors"
Shoukou Lee, Chihiro Shinji, Kiyoshi Ogura, Motomu Shimizu, Satoko Maeda, Mayumi
Sato, Minoru Yoshida, Yuichi Hashimoto and Hiroyuki Miyachi
Bioorg. Med. Chem. Lett., 2007, 17(17), 4895-4900. |
"3,3-Diphenylpentane skeleton as a steroid skeleton substitute:
Novel inhibitors of human 5α-reductase 1"
Shinnosuke Hosoda and Yuichi Hashimoto
Bioorg. Med. Chem. Lett., 2007, 17(19), 5414-5418. |
"Structural development of liver X receptor (LXR) antagonists derived
from thalidomide-related glucosidase inhibitors"
Tomomi Noguchi-Yachide, Hiroyuki Miyachi, Hiroshi Aoyama, Atsushi Aoyama,
Makoto Makishima and Yuichi Hashimoto
Chem. Pharm. Bull., 2007, 55(12), 1750-1754. |
"Nucleophilic asymmetric epoxidation catalyzed by cyclic guanidines"
Tetsuya Kita, Bongki Shin, Yuichi Hashimoto and Kazuo Nagasawa
Heterocycles, 2007, 73, 241-247. |
"Direct ortho cupration: A new route to regioselectively functionalized
aromatics"
Shinya Usui, Yuichi Hashimoto, James V. Morey, Andrew E. H. Wheatley and Masanobu Uchiyama
J. Am. Chem. Soc., 2007, 129(49), 15102-15103. |
"Design, synthesis, and evalution of non-steroidal farnesoid X receptor (FXR) antagonist"
Kainuma, M., Makishima, M., Hashimoto, Y. and Miyachi, H.
Bioorg. Med. Chem., 2007, 15(7), 2587-2600. |
"Synthesis and biological activities of batzelladine derivatives"
Shimokawa, J., Iijima, Y., Hashimoto, Y., Chiba, H., Tanaka, H. and Nagasawa, K.
Heterocycles, 2007, 72, 145-150. |
"Design, synthesis, and evaluation of characteristic subtype-selective peroxisome proliferator-activated receptor (PPAR) ligands"
Miyachi H.
Current Med. Chem., 2007, 14(22), 2335-2343. |
"大学における科学活動としての医薬化学：ドラマタイプ手法とマルチテンプレート手法の発信"
橋本祐一
MEDCHEM MEWS, 2007, 17(1), 20-23. |
"「大学院講義有機化学演習編」，Ⅱ?Ⅲ 生物有機化学"
橋本祐一
大学院講義有機化学演習編, （野依良治・柴崎正勝・鈴木啓介・玉夫皓平・中筋一弘・奈良坂紘一 編）、東京化学同人、東京、pp75-80, pp170-176,2007, 17(1), 20-23. |
"核内レセプターリガンドの創製研究"
宮地弘幸，橋本祐一
「化学フロンディァ⑲創薬をめざす有機合成戦略 --- 進化する医薬品づくり」, （宍戸宏造・新藤充 編）、化学同人，京都、p149-155 (2007). |
"創薬研究の基礎知識---標的となる生体分子"
橋本祐一
ベーシック薬学教科書シリーズ６「創薬科学・医薬化学」, （橘高敦史 編）、化学同人、京都、第6章, p95-131 (2007). |
"代表的な医薬品---気管支喘息治療薬、消化性潰瘍薬、糖尿病治療薬"
橋本祐一
ベーシック薬学教科書シリーズ６「創薬科学・医薬化学」, （橘高敦史 編）、化学同人、京都、第11-13章, p217-248 (2007). |
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