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2001年



"Asymmetric synthesis of a 3-acyltetronic acid derivative,RK-682,and formation of its calcium salt during silica gel colimn chromatography"
M. Sodeoka, R. Sampe, S. Kojima, Y. Baba, N. Morisaki, and Y. Hashimoto
Chem. Pharm. Bull., 49, 206-212, (2001)
"Specific inhibitor of puromycin-sensitive aminopeptidase with a homophthalimide skeleton: Identification of the target molecule and a structure-activity relationship study"
M. Komoda, H. Kakuta, H. Takahashi, Y. Fujimoto, S. Kadoya, F. Kato, and Y. Hashomoto
Biol. Med. Chem., 9, 121-131, (2001)
"Glycosylative inactivation of chalcomycin and tylosin by a clinically isolated Nocardia asteroides strain"
N. Morisaki, Y. Hashimoto, K. Furihata, K. Yazawa, M. Tamura and Y. Mikami
J. Antibiotics, 54, 157-165, (2001)
"Formaldehyde-mediated Modification of natural deoxyguanosine with amines: One-pot cyclization as a molecular model for genotoxicity"
H. Takahashi, and Y. Hashimoto
Bioorg. Med. Chem. Lett., 729-731, 11, (2001)
"α-Glucosidase inhibitors with a 4,5,6,7-tetrachlorophthalimide skeleton pendanted with a cycloalkyl or dicarba-cloro-dodecaborane group"
S. Sou, H. Takahashi, R. Yamasaki, H. Kagechika, Y. Endo, and Y. Hashimoto
Chem. Pharm. Bull., 49, 791-793, (2001)
"Thymidine phosphorylase inhibitors with a homophthalimide skelaton"
T. Kita, H.Takahashi, and Y. Hashimoto
Biol. Pharm. Bull., 24, 860-862, (2001)
"Aminopeptidase inhibitors: 3-(2,6-diethylphenyl)-2,4(1H,3H) quinazolinedione and N-(2,6-diethylphenyl)-2-amino-4H-3,1-benzoxazin-4-one"
H. Kakuta, Y. Koiso, H. Takahashi, K. Nagasawa, and Y. Hashimoto
Heterocycles, 55, 1433-1438, (2001)
"A new macrocyclic trichothecene, 12, 13-deoxyroridin E, produced by the marine-derived fungus Myrothecium roridum collected in Palau"
M. Namikoshi, K. Akano, S. Meguro, I. Kasuga, Y. Mine, T. Takahashi and H. Kobayashi
J. Nat. Prod., 64, 396-398, (2001)
"Novel formaldehyde-mediated dimerization reaction of N-alkyl-1-naphthylamine derivatives under mild/neutral conditions; Application to synthesis of naphthylamine-derived macrocycles"
H. Takahashi, Y. Hashimoto, and K. Nagasawa
Heterocycles, 55, 2305-2313, (2001)
"Enzyme inhibitors derived from thalidomide"
H. Kakuta, H. Takahashi, S. Sou, T. Kita, K. Nagasawa and Y. Hashimoto
Recent Res. Devel. Medicinal Chem., 1, 189-211, (2001)