本文へジャンプ

1998年



"Photoaffinity labeling of RARs and mapping of labeled sites by an endoproteinase combination technique"
Y. Hashimoto, and T. Sasaki
Methods in Molecular Biology, 89, 293-305, (1998)
"Novel potent nonpeptide aminopeptidase N inhibitors with a cyclic imide skeleton"
H. Miyachi, M. Kato, J. Kato, and Y. Hashimoto
J. Med. Chem., 41, 263-265, (1998)
"レチノイドによるがんの治療と予防をめぐる話題"
影近弘之, 萩本啓文, 森脇久隆, 橋本祐一(座談会)
ファルマシア, 34, 213-218, (1998)
"Sequence selective interaction between nucleotides and intercalators bound to water soluble dextran: An application to the affinity chromatography of dinucleotides"
R. Shirai, T. Ito, S. Iwasaki, and Y. Hashimoto
Nucleos. & Nucleot., 17, 593-601, (1998)
"Isolation and structure of an antimitotic cyclic peptide, ustiloxin F: Chemical interrelation with homologous peptide, ustiloxin B"
Y. Koiso, N. Morisaki, Y. Yamashita, Y. Mitsui, R. Shirai, Y. Hashimoto and S. Iwasaki
J. Antibiotics, 51, 418-422, (1998)
"Synthesis and anti-tubulin activity of ustiloxin D derivatives"
N. Morisaki, Y. Mitsui, Y. Yamashita, Y. Koiso, R. Shirai, Y. Hashimoto and S. Iwasaki
J. Antibiotics, 51, 423-427, (1998)
"Specific detection of phosphatidylinositol 3,4,5-trisphosphate binding proteins by the PIP3 analogue beads: An application for rapid purification of the PIP3 binding proteins"
T. Shirai, K. Tanaka, Y. Terada, T. Sawada, R. Shirai, Y. Hashimoto, S. Nagata, A. Iwamatsu, K.Okawa, S. Li, S. Hattori, H. Mono, Y. Fukui
Biochim. Biophys. Acta, 1402, 292-302, (1998)
"Novel biological respose modifiers derived from thalidomide"
Y. Hashimoto
Current Med. Chem., 5, 163-178, (1998)
"Enhanced potency of perfluorinated thalodomide derivatives for inhibition of LPS-induced tumor necrosis factor-a production is associated with a change of mechanism of action"
S. Niwayama, C. Loh, B. E. Turk, J. O. Liu, H. Miyachi and Y. Hashimoto
Bioorg. Med. Chem. Lett., 8, 1071-1076, (1998)
"Potent retinoid synergists with a diphenylamine skeleton"
K. Ohta, M. Tsuji, E. Kawachi, H. Fukasawa, Y. Hashimoto, K. Shudo and H. Kagechika
Biol. Pharm. Bull., 21, 544-546, (1998)
"Novel thiazolidinedione derivatives with retinoid synergistic activity"
M. Ebisawa, E. Kawachi, H. Fukasawa, Y. Hashimoto, A. Itai, K. Shudo and H. Kagechika
Biol. Pharm. Bull., 21, 547-549, (1998)
"Tumor necrosis factor-alpha production enhancing activity of substituted 3'-methylthalidomide: Influence of substituents at the phthaloyl moiety on the activity and stereoselectivity"
H. Miyachi, Y. Koiso, R. Shirai, S. Niwayama, J. O. Liu and Y. Hashimoto
Chem. Pharm. Bull., 46, 1165-1168, (1998)
"Novel DNA minor groove binding with an aromatic layered structure"
A. Tanatani, R. Fukutomi, H. Kakuta, N. Tomioka, A. Itai, Y. Hashimoto, K. Shudo and H. Kagechika
Nucleic Acids Symp. Ser., 39, 31-32, (1998)
"Asymmetric synthesis of antimitotic combretadioxolane with potent antitumor activity against multi-drug registant cells"
R. Shirai, H. Takayama, A. Nishikawa, Y. Koiso and Y. Hashimoto
Bioorg. Med. Chem. Letters 8, 1997-2000, (1998)
"Aromatic layered guanidines bind sequence-specifically to DNA minor groove with precise fit"
R. Fukutomi, A. Tanatani, H. Kakuta, N. Tomioka, A. Itai, Y. Hashimoto, K. Shudo and H. Kagechika
Tetrahedron Lett., 39, 6475-6778, (1998)
"Synthesis of 6-amylsalitilic acid from 3-anisaldehyde: conversion of phthalide to thiophthalide by aluminium halide-butanethiol"
A. Nishikawa, Y. Hashimoto and R. Shirai
Tetrahedron Lett., 39, 7307-7308, (1998)
"Synthesis of diacylglycerol analog of phosphatidylinositol 3,4,5-triphosphate"
R. Shirai, K. Morita, A. Nishikawa, N. Nakatsu, Y. Fukui, N. Morisaki and Y. Hashimoto
Tetrahedron Lett., 39, 9485-9488, (1998)
"Collisionally activated dissociation of 13-membered peptides, ustiloxins and phomopsins"
N. Morisaki, Y. Koiso, Y. Mitsui, Y. Yamashita, H. Kobayashi, R. Shirai, Y. Hashimoto and S.Iwasaki
J. Mass Spectrom. Soc. Jpn., 46, 495-501, (1998)
"Purification and cDNA cloning of cytokinin-specific binding protein from mung bean(Vigna radiata)"
Y. Fujimoto, R. Nagata, H. Fukasawa, K. Yano, M. Azuma, A. Iida, S. Sugimoto, K. Shudo and Y.Hashimoto
Eur. J. Biochem., 258, 794-802, (1998)
"生物活性発現の分子機構"
橋本祐一
「大学院講義有機化学,II巻,有機合成化学・生物有機化学」,
野依良治・柴崎正勝・鈴木啓介・玉尾皓平・中筋一弘・奈良坂紘一編,
東京化学同人, p409-431, (1998)