• Crystallographic analysis of the overlapping dinucleosome as a novel chromatin unit.

  Nishimura M, Nozawa K, Kurumizaka H.
  Biophysics and Physicobiology. Volume 15 Pages 251-254 2018 Dec 19. doi:10.2142/biophysico.15.0_251

• CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.

  Snijders Blok L, et al.
  Nat Commun. 2018 Nov 5;9(1):4619.

• Structural basis of the nucleosome transition during RNA polymerase II passage.

  Kujirai T, Ehara H, Fujino Y, Shirouzu M, Sekine S, Kurumizaka H.
  Science. 2018 Oct 4. pii: eaau9904. doi: 10.1126/science.aau9904. Epub 2018 Oct 4.

  本論文は、新着論文レビューに掲載されました。
• Methods for Preparing Nucleosomes Containing Histone Variants.

  Kujirai T, Arimura Y, Fujita R, Horikoshi N, Machida S, Kurumizaka H.
  Methods Mol Biol. 2018;1832:3-20. doi: 10.1007/978-1-4939-8663-7_1.

• Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.

  Arimura Y, Ikura M, Fujita R, Noda M, Kobayashi W, Horikoshi N, Sun J, Shi L, Kusakabe M, Harata M, Ohkawa Y, Tashiro S, Kimura H, Ikura T, Kurumizaka H.
  Nucleic Acids Res. 2018 Jul 24. doi: 10.1093/nar/gky661.

• Structural polymorphism of the Escherichia coli poly-α-L-glutamate synthetase RimK.

  Arimura Y, Kono T, Kino K, Kurumizaka H.
  Acta Crystallogr F Struct Biol Commun. 2018 Jul 1;74(Pt 7):385-390. doi: 10.1107/S2053230X18007689.

• Histone H2A variants confer specific properties to nucleosomes and impact on chromatin accessibility.

  Osakabe A, Lorkovic ZJ, Kobayashi W, Tachiwana H, Yelagandula R, Kurumizaka H, Berger F.
  Nucleic Acids Res. 2018 Jun 26. doi: 10.1093/nar/gky540.

• Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2.

  Higgs MR, Sato K, Reynolds JJ, Begum S, Bayley R, Goula A, Vernet A, Paquin KL, Skalnik DG, Kobayashi W, Takata M, Howlett NG, Kurumizaka H, Kimura H, Stewart GS.
  Mol Cell. 2018 Jun 7; pii: S1097-2765(18)30392-7.

• MNase, as a probe to study the sequence-dependent site exposures in the +1 nucleosomes of yeast.

  Luo D, Kato D, Nogami J, Ohkawa Y, Kurumizaka H, Kono H.
  Nucleic Acids Res. 2018 Jun 11. doi: 10.1093/nar/gky502.

• Structural Diversity of Nucleosomes Characterized by Native Mass Spectrometry.

  Saikusa K, Osakabe A, Kato D, Fuchigami S, Nagadoi A, Nishimura Y, Kurumizaka H, Akashi S.
  Anal Chem. 2018 Jun 12. doi: 10.1021/acs.analchem.8b01649.

• Structural Basis of Homology-directed DNA Repair Mediated by RAD52.

  Saotome M, Saito K, Yasuda T, Ohtomo H, Sugiyama S, Nishimura Y, Kurumizaka H, Kagawa W
  iScience 2018 May 25;3:50-62.

• Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.

  Harada A, Maehara K, Ono Y, Taguchi H, Yoshioka K, Kitajima Y, Xie Y, Sato Y, Iwasaki T, Nogami J, Okada S, Komatsu T, Semba Y, Takemoto T, Kimura H, Kurumizaka H, Ohkawa Y.
  Nat Commun. 2018 Apr 11;9(1):1400. doi: 10.1038/s41467-018-03845-1.

• Cryo-EM structure of the nucleosome containing the ALB1 enhancer DNA sequence.

  Takizawa Y, Tanaka H, Machida S, Koyama M, Maehara K, Ohkawa Y, Wade PA, Wolf M, Kurumizaka H.
  Open Biol. 2018 Mar;8(3). pii: 170255. doi: 10.1098/rsob.170255.

• LC-MS/MS-based quantitative study of the acyl group- and site-selectivity of human sirtuins to acylated nucleosomes.

  Tanabe K, Liu J, Kato D, Kurumizaka H, Yamatsugu K, Kanai M, Kawashima SA.
  Sci Rep. 2018 Feb 8;8(1):2656. doi: 10.1038/s41598-018-21060-2.

• Structural Basis of Heterochromatin Formation by Human HP1

  Machida S, Takizawa Y, Ishimaru M, Sugita Y, Sekine S, Nakayama J, Wolf M, Kurumizaka H.
  Mol Cell. 2018 Feb 1;69:1–13.

  本論文は、新着論文レビューに掲載されました。
• Structural diversity of the nucleosome.

  Koyama M, Kurumizaka H.
  J Biochem. 2018 Feb 1;163(2):85-95. doi: 10.1093/jb/mvx081.

  本論文は、掲載されたジャーナルの表紙を飾りました。詳しくはこちらから
• Replication stress induces accumulation of FANCD2 at central region of large fragile genes.

  Okamoto Y, Iwasaki WM, Kugou K, Takahashi KK, Oda A, Sato K, Kobayashi W, Kawai H, Sakasai R, Takaori-Kondo A, Yamamoto T, Kanemaki MT, Taoka M, Isobe T, Kurumizaka H, Innan H, Ohta K, Ishiai M, Takata M.
  Nucleic Acids Res.2018 Apr 6;46(6):2932-2944. doi: 10.1093/nar/gky058.

• Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders.

  Shiraishi K, Shindo A, Harada A, Kurumizaka H, Kimura H, Ohkawa Y, Matsuyama H.
  Andrology. 2018 Jan;6(1):158-165. doi: 10.1111/andr.12438. Epub 2017 Nov 27.

• SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites.

  Fukuto A, Ikura M, Ikura T, Sun J, Horikoshi Y, Shima H, Igarashi K, Kusakabe M, Harata M, Horikoshi N, Kurumizaka H, Kiuchi Y, Tashiro S.
  Nucleus. 2018 Jan 1;9(1):87-94. doi: 10.1080/19491034.2017.1395543. Epub 2017 Dec 14.