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発表論文 Publications1995Kinoshita, T., Yokota, T., Arai, K., and Miyajima, A. (1995) Suppression of apoptotic death in hematopoietic cells by signaling through the IL-3 and GM-CSF receptors. EMBO. J. 14, 266-275.Ichihara, M., Hara, T., Takagi, M., Cho, L, Gorman, D., and Miyajma, A. (1995) Impaired interleukin 3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor a subunit gene. EMBO J. 14, 939-950. Takagi, M., Hara T., Ichihara M., Takatsu K., and Miyajima A. (1995) Multi-colony stimulating activity of interleukin-5 (IL-5) on hematopoietic progenitors from transgenic mouse that express IL-5 receptor a subunit consititutively. J. Exp. Med. 181, 889-899 Kinoshita T., Yokota T., Arai K., and Miyajima A. (1995) Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells Oncogene 10, 2207-2212. Yoshimura, A., Ohkubo, T., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Hara, T., and Miyajima, A. (1995) A novel cytokine-inducible gene encodes an SH2-containing protein that binds to the tyrosine phosphorylated interleukin-3 and erythropoietin receptors. EMBO J. 14, 2816-2826. Mui, A. L-F., Wakao, H., Harada, N., O'Farrell, A-M., and Miyajima, A. (1995) Interleukin-3, granulocyte-macrophage colony stimulating factor, and interleukin-5 transduce signals through two STAT5 homologues. EMBO J. 14, 1166, -1175. Nishinakamura R., Nakayama N., Hirabayashi Y., Inoue T., Aud D., McNeil T., Azuma S., Yoshida S., Toyoda Y., Arai K., Miyajima A. and Murray R. (1995) Mice deficient for the IL-3/GM-CSF/IL-5 bc recepor exhibit lung pathology and impaired immune response, while bIL3 receptor-deficient mice are normal. Immunity 2, 211-222. Hara, T., Ichihara, M., Takagi, M., and Miyajima, A. (1995) Interleukin-3 (IL-3) nonresponder inbred mouse strains carry the identical deletion of a branch point in the the IL-3 receptor a subunit gene. Blood 85, 2331-2336. Wakao, H., Harada, N., Kitamura, T., Mui, A.L., and Miyajima, A. (1995) Interleukin-2 and erythropoietin activate STAT5 via distinct pathways. EMBO J. 14, 2527-2535. Hara, T., Bacon, K.B., Cho, L.C., Yoshimura, A., Morikawa, Y., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Schall, T. J., and Miyajima, A. (1995) Molecular cloning and functional characterization of a novel member of the C-C chemokine family. J. Immunol. 155, 5352-5358. Damen, J. E., Wakao, H., Miyajima A., Krosl, J., Humphries, R. K., Culter, R. L. and Krystal, G. (1995) Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and STAT5 activation. EMBO J. 14. 5557-5568. Kitamura T., Onishi M., Kinoshita S., Shibuya A., Miyajima A., and Nolan G.P. (1995) Efficient screening of retroviral cDNA expression libraries. Proc. Natl. Acad. Sci. USA. 92, 9146-9150. 1994Kitamura, T., Ogorochi, T., and Miyajima, A. (1994) Multimeric cytokine receptors. Trends in Endocrinology and Metabolism. 5, 8-14.1993Miyajima, A., Mui, A., Ogorochi, T., and Sakamaki, K. (1993) The receptors for granulocyte-macrophage colony stimulating factor, interleukin 3 and interleukin 5. Blood 82, 1960-1974.Sato, N., Sakamaki, K., Terada, N., Arai, K., and Miyajima, A. (1993) Signal transduction by the high affinity GM-CSF receptor: two distinct cytoplasmic domains of the common b subunit responsible for different signaling. EMBO J. 12, 4181-4189. 1992Miyajima, A., Hara, T., and Kitamura, T. (1992) Common subunits of cytokine receptors and the functional redundancy of cytokines. Trends in Biochemical Science 17, 378-382.Hara, T., and Miyajima, A. (1992) Two distinct functional high affnity murine IL-3 receptors EMBO J. 11, 1875-1884. Miyajima, A., Kitamura, T., Harada, N., Yokota, T., and Arai, K. (1992) Cytokine receptors and signal transduction. Ann. Rev. Immunol. 10, 295-331. 1991Kitamura, T., Sato, N., Arai, K., and Miyajima, A. (1991) Expression cloning of the human IL-3 receptor cDNA reveals a shared b subunit for the human IL-3 and GM-CSF receptors. Cell 66, 1165-1174.Kitamura, T., Hayashida, K., Sakamaki, K., Yokota, T., Arai, K., and Miyajima, A. (1991) Reconstitution of functional receptors for human granulocyte/macrophage colony stimulating factor (GM- CSF): Evidence that AIC2B is a subunit of murine GM-CSF receptor. Proc. Natl. Acad. Sci. USA 88, 5082-5086. 1990Hayashida, K., Kitamura, T., Gorman, D. M., Arai, K., Yokota, T., and Miyajima, A. (1990) Molecular cloning of a second subunit of the humna GM-CSF receptor: Reconstitution of a high affinity GM-CSF receptor. Proc. Natl. Acad. Sci. USA 87, 9655- 9659.Gorman, D.M., Itoh, N., Kitamura, T., Schreurs, J., Yonehara, S., Yahara, I., Arai. K., and Miyajima, A. (1990) Cloning and expression of a novel IL-3 receptor-like gene: identification of another member of the cytokine receptor gene family. Proc. Natl Acad. Sci. USA 87. 5459-6463. Itoh, N., Yonehara, S., Schreurs, J., Gorman, M.D., Maruyama, K., Ishii, A., Yahara, I., Arai, K., and Miyajima, A. (1990) Cloning of an interleukin-3 receptor gene: a member of a distinct receptor gene family. Science. 247, 324-327. Harada, N., Castle, B.E., Gorman, D.M., Itoh, N., Schreurs, J., Barrett, R.L., Howard, M., and Miyajima, A. (1990) Expression cloning of a cDNA encoding the murine interleukin-4 receptor based on ligand binding. Proc. Natl. Acad. Sci. USA 87, 857 -861. |
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