IQB Annual Report 2019
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. | Acta Crystallogr D Struct Biol. Structure determination of the nucleosome core particle by selenium SAD phasing. Saotome M, Horikoshi N, Urano K, Kujirai T, Yuzurihara H, Kurumiza-ka H, Kagawa W.. | Bioorganic & Medic-inal Chemistry Application of Protein Knock-down Strategy Targeting β-Sheet Structure to Multiple Disease-as-sociated Polyglutamine Proteins.Yamashita H, Tomoshige S, Nomura S, Ohgane K, Hashimoto Y, Ishikawa M.. | The American Journal of Human Genetics Missense Mutations in NKAP Cause a Disorder of Transcrip-tional Regulation Characterized by Marfanoid Habitus and Cognitive Impairment.Fiordaliso SK, Iwata-Otsubo A, Ritter AL, Quesnel-Vallières M, Fujiki K, Nishi E, Hancarova M, Miyake N, Morton JEV, Lee S, Hackmann K, Bando M, Masuda K, Nakato R, Arakawa M, Bhoj E, Li D, Hakonarson H, Takeda R, Harr M, Keena B, Zackai EH, Okamoto N, Mizuno S, Ko JM, Valachova A, Prchalova D, Vlckova M, Pippucci T, Seiler C, Choi M, Matsumoto N, Di Donato N, Barash Y, Sedlacek Z, Shirahige K, Izumi K.. | Oncogene. UHRF-KAT-mediated regula-tion of TUSC expression via histone methylation/acetylation is critical for the proliferation of colon cancer cells.Taniue K, Hayashi T, Kamoshida Y, Kurimoto A, Takeda Y, Negishi L, Iwasaki K, Kawamura Y, Goshima N, Akiyama T.. | Mol Cell Biol. The CCR-NOT Complex Main-tains Stability and Transcription of rRNA Genes by Repressing Antisense Transcripts.Hosoyamada S, Sasaki M, Kobayashi T.. | Dierentiation. Metabolomic proling during the dierentiation of human induced pluripotent stem cells into hepatocyte-like cells.Jellali R, Lereau Bernier M, Tauran Y, Gilard F, Danoy M, Kido T, Miyajima A, Sakai Y, Leclerc E.. | Mol Omics. Analysis of the transcription factors and their regulatory roles during a step-by-step dierentia-tion of induced pluripotent stem cells into hepatocyte-like cells.Tauran Y, Poulain S, Lereau-Berni-er M, Danoy M, Shinohara M, Segard BD, Kato S, Kido T, Miyajima A, Sakai Y, Plessy C, Leclerc E.. | Epigenetics Chroma-tin. Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells. Epigenetics Chromatin.Nakato R, Wada Y, Nakaki R, Nagae G, Katou Y, Tsutsumi S, Nakajima N, Fukuhara H, Iguchi A, Kohro T, Kanki Y, Saito Y, Kobayashi M, Izumi-Taguchi A, Osato N, Tatsuno K, Kamio A, Hayashi-Takanaka Y, Wada H, Ohta S, Aikawa M, Nakajima H, Nakamura M, McGee RC, Heppner KW, Kawakatsu T, Genno M, Yanase H, Kume H, Senbonmatsu T, Homma Y, Nishimura S, Mitsuyama T, Aburatani H, Kimura H, Shirahige K.. | Nucleic Acids Res.Incorporation and inuence of Leishmania histone H in chromatin.Dacher M, Tachiwana H, Horikoshi N, Kujirai T, Taguchi H, Kimura H, Kurumizaka H.. | Immun Inamm Dis. Higher incidence of zinc and nickel hypersensitivity in patients with irritable bowel syndrome.Kageyama Y, Aida K, Kawauchi K, Morimoto M, Akiyama T, Nakamu-ra T.. | Genes Genet Syst. Defects in the NuA acetyltrans-ferase complex increase stability of the ribosomal RNA gene and extend replicative lifespan.Wakatsuki T, Sasaki M, Kobayashi T.. | J Biol Chem. Glucocorticoids potentiate the inhibitory capacity of programmed cell death by up-regulating its expression on T cells.Maeda N, Maruhashi T, Sugiura D, Shimizu K, Okazaki IM, Okazaki T.. | Adv Exp Med Biol. Stimulatory and Inhibitory Co-signals in Autoimmunity.Okazaki T, Okazaki IM.. | Curr Opin Struct Biol. Transcription through the nucleosome.Kujirai T, Kurumizaka H.. | Structure. Cryo-EM Structures of Centro-meric Tri-nucleosomes Contain-ing a Central CENP-A Nucleo-some.Takizawa Y, Ho CH, Tachiwana H, Matsunami H, Kobayashi W, Suzuki M, Arimura Y, Hori T, Fukagawa T, Ohi MD, Wolf M, Kurumizaka H.21IQB Institute for Quantitative Biosciences |

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