IQB Annual Report 2020
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| IQB Institute for Quantitative Biosciences30����.� | PLOS Genetics Meiotic cohesins mediate initial loading of HORMAD� to the chromosomes and coordinate SC formation during meiotic prophase.Fujiwara Y, Horisawa YT, Inoue E, Tani N, Shibuya H, Fujimura S, Kariyazono R, Sakata T, Ohta K, Araki K, Okada Y, Ishiguro KI����.� | Cell Metab. Generation of a p�� Reporter Mouse and Its Use to Characterize and Target p��high Cells In Vivo.Omori S, Wang TW, Johmura Y, Kanai T, Nakano Y, Kido T, Susaki EA, Nakajima T, Shichino S, Ueha S, Ozawa M, Yokote K, Kumamoto S, Nishiyama A, Sakamoto T, Yamaguchi K, Hatakeyama S, Shimizu E, Katayama K, Yamada Y, Yamazaki S, Iwasaki K, Miyoshi C, Funato H, Yanagisawa M, Ueno H, Imoto S, Furukawa Y, Yoshida N, Matsushima K, Ueda HR, Miyajima A, Nakanishi M.����.�� | Sci Rep. Essential roles of oncostatin M receptor β signaling in renal crystal formation in mice.Yamashita S, Komori T, Kohjimoto Y, Miyajima A, Hara I, and Morikawa Y.����.�� | J Mol Biol.Contributions of histone variants in nucleosome structure and function.Kurumizaka H, Kujirai T, Takizawa Y.����.�� | Human Gene Thera-pyAspects of Gene Therapy Prod-ucts Using Current Genome-Edit-ing Technology in Japan.Yamaguchi T, Uchida E, Okada T, Ozawa K, Onodera M, Kume A, Shimada T, Takahashi S, Tani K, Nasu Y, Mashimo T, Mizuguchi H, Mitani K, Maki K.����.�� | Cell Rep.Essentiality of CENP-A Depends on Its Binding Mode to HJURP.Hori T, Cao J, Nishimura K, Ariyoshi M, Arimura Y, Kurumiza-ka H, Fukagawa T.����.�� | Science Structural basis for the inhibition of cGAS by nucleosomes.Kujirai T, Zierhut C, Takizawa Y, Kim R, Negishi L, Uruma N, Hirai S, Funabiki H, Kurumizaka H.����.�� | Mol. Cell. Biol. Age-dependent ribosomal DNA variations in mice.Watada E, Li S, Hori Y, Fujiki K, Shirahige K, Inada T, Kobayashi T.����.�� | Development, Growth & Differentiation Diverse sensory cues for individ-ual recognition.Chung M, Wang MY, Huang Z, Okuyama T.����.�� | Nucleic Acids Res. Acetylation-modulated communi-cation between the H� N-terminal tail domain and the intrinsically disordered H� C-terminal domain. Hao F, Murphy KJ, Kujirai T, Kamo N, Kato J, Koyama M, Okamato A, Hayashi G, Kurumizaka H, Hayes JJ.����.�� | Ann Rheum Dis. Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis.Tsuchiya H, Ota M, Sumitomo S, Ishigaki K, Suzuki A, Sakata T, Tsuchida Y, Inui H, Hirose J, Kochi Y, Kadono Y, Shirahige K, Tanaka S, Yamamoto K, Fujio K.����.�� | RNA siRNA potency enhancement via chemical modifications of nucleotide bases at the �ʼ-end of the siRNA guide strand.Shinohara F, Oashi T, Harumoto T, Nishikawa T, Takayama Y, Miyagi H, Takahashi Y, Nakajima Y, Sawada Y, Koda Y, Makino A, Sato A, Hamaguchi K, Suzuki M, Yamamoto J, Tomari Y, Saito JI.����.�� | RNA Mechanistic analysis of the enhanced RNAi activity by �-mCEPh-purine at the �ʼ end of the siRNA guide strand.Brechin V, Shinohara F, Saito JI, Seitz H, Tomari Y.����.�� | Nature Communica-tions Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence.Olan I, Parry AJ, Schoenfelder S, Narita M, Ito Y, Chan ASL, Slater GSC, Bihary D, Bando M, Shirahige K, Kimura H, Samarajiwa SA, Fraser P, Narita M.����.�� | DermatologyDysbiosis of Oral Microbiota Associated with Palmoplantar Pustulosis.Kageyama Y, Shimokawa Y, Kawauchi K, Morimoto M, Aida K, Akiyama T, Nakamura T.

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