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Takashi Sutani (Ph.D.) Associate Professor Laboratory of Genome Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo

1999 Degree of Ph.D. (Science), Kyoto University
2000- Harvard Medical School; Postdoctoral Fellow
2005- Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology; Researcher/Research Associate
2010- The University of Tokyo, Institute of Molecular and Cellular Biosiences; Research Associate/Assistant Professor
2020- current position

I am studying the mechanism of how genomic DNA is inherited to the next generation.
In particular, the roles of SMC complexes, modulators of higher-order DNA structures, in the maintenance and inheritance of genetic information are the major research topics.
Recently, I have also started to study the human microbiota, bacterial communities that live on the human body surface.
Research tools; NGS-based technologies (ex. ChIP-seq, Hi-C), bioinformatics, mathematical modeling.

• Masuda K, Renard-Guillet C, Shirahige K, Sutani T.
  Bioinformatical dissection of fission yeast DNA replication origins.
  Open Biol. (2020) 10:200052
• Suzuki T, Sutani T, Nakai H, Shirahige K, Kinoshita S.
  The Microbiome of the Meibum and Ocular Surface in Healthy Subjects.
  Invest Ophthalmol Vis Sci. (2020) 61:18
• Minamino M, Tei S, Negishi L, Kanemaki MT, Yoshimura A, Sutani T, Bando M, Shirahige K.
  Temporal Regulation of ESCO2 Degradation by the MCM Complex, the CUL4-DDB1-VPRBP Complex, and the Anaphase-Promoting Complex.
  Curr Biol. (2018) 28:2665-2672.e5.
• Sakata T, Shirahige K, Sutani T.
  ChIP-seq Analysis of Condensin Complex in Cultured Mammalian Cells.
  Methods Mol Biol. (2017) 1515:257-271.
• Pakchuen S, Ishibashi M, Takakusagi E, Shirahige K, Sutani T.
  Physical Association of Saccharomyces cerevisiae Polo-like Kinase Cdc5 with Chromosomal Cohesin Facilitates DNA Damage Response.
  J Biol Chem. (2016) 291:17228-17246
• Sutani T, Sakata T, Nakato R, Masuda K, Ishibashi M, Yamashita D, Suzuki Y, Hirano T, Bando M, Shirahige K.
  Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation.
  Nat Commun. (2015) 6:7815

• tsutani_AT_iqb.u-tokyo.ac.jp (Please replace "_AT_" with "@".)